Nr1i2 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comNr1i2 Polyclonal Antibody for Rat(Rattus norvegicus)

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Index > Protein center > Nr1i2(Gene name) > Rat

Nr1i2 (Gene name),

Nuclear receptor subfamily 1 group I member 2 (Protein name ), NR1I2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Nr1i2(Pxr);

Protein name:

Nuclear receptor subfamily 1 group I member 2;

Alternative:

Pregnane X receptor;Orphan nuclear receptor PXR;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimer with RXRA. Interacts with NCOA1.

Function:

Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific ligands is species-specific, due to differences in the ligand-binding domain. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

431

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

431:

NAQQTQQLLR | IQDTHPFATP | LMQELFSSTD | G

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.207164

SMR:

Q9R1A7

Pfam:

PF00104

KEGG:

rno:84385

String:

Q9R1A7

Uniprot:

Q9R1A7

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ELISA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

E10641m

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

E10641h

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Packing:

96T

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ELISA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

E10641r

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96T

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CLIA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

U10641h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

U10641m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

U10641r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Nuclear receptor subfamily 1 group I member 2

Cat.:

P10641Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Nuclear receptor subfamily 1 group I member 2

Protein for Rat Nuclear receptor subfamily 1 group I member 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation."
Zhang H. , LeCulyse E. , Liu L. , Hu M. , Matoney L. , Zhu W. , Yan B.
Arch. Biochem. Biophys.368:14-22(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.

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